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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54400. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent manner through recruitment of functional TLE5 complexes to DNA. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Pf1; PHD factor 1; PHD finger protein 12; PHD zinc finger transcription factor; PHF12; PHF12 (HGNC:20816)
基因别名: KIAA1523; PF1; PHF12
UniProt ID: (Human) Q96QT6
Entrez Gene ID: (Human) 57649