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Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54103. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CTD-binding SR-like protein rA9; PHD and RING finger domain-containing protein 1; protein phosphatase 1, regulatory subunit 125
基因别名: KIAA1542; PHRF1; PPP1R125; RNF221
UniProt ID: (Human) Q9P1Y6
Entrez Gene ID: (Human) 57661