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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67389. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
PI4KB and PI4KA are the two human type III PI4 kinases, which share sequence similarly with PI3 kinases and phosphorylate the 4 position of phosphotidyl inositol. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by PI4KA is a type III enzyme that is not inhibited by adenosine. Two transcript variants encoding different isoforms have been described for PI4KA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: phosphatidylinositol 4-kinase; phosphatidylinositol 4-kinase 230; Phosphatidylinositol 4-kinase alpha; Phosphatidylinositol 4-Kinase III alpha; phosphatidylinositol 4-kinase, catalytic, alpha; phosphatidylinositol 4-kinase, type III, alpha; PI4-kinase alpha; ptdIns-4-kinase alpha; testicular secretory protein Li 35
基因别名: PI4K-ALPHA; pi4K230; PI4KA; PIK4; PIK4CA; PMGYCHA
UniProt ID: (Human) P42356
Entrez Gene ID: (Human) 5297