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Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57757. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for this gene. A pseudogene on chromosome 11 has also been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 2.4.1.198; Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Phosphatidylinositol-glycan biosynthesis class C protein; phosphatidylinositol-glycan biosynthesis, class C protein; PIG-C
基因别名: GPI2; PIGC
UniProt ID: (Human) Q92535
Entrez Gene ID: (Human) 5279