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产品信息
RP-43087
产品规格
种属
Human
分子量
72 kDa
分类
Native
类型
Protein
活性
Specific Activity = 6.7 U/mg; determined that 1 unit equals the prothrombin activity in 1 mL of normal human plasma.
偶联物
形式
Liquid
浓度
8 mg/mL
纯化类型
SDS-PAGE
保存液
50% water with 50% glycerol
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
RP-43087 contains native human Prothrombin protein.
RP-43087 may be used as a positive control in many immunological assays.
The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests.
This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!
靶标信息
Prothrombin or Coagulation factor II, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activation peptide fragment 1; Activation peptide fragment 2; Coagulation factor II; coagulation factor II (thrombin); prepro-coagulation factor II; Prothrombin; prothrombin B-chain; serine protease; Thrombin heavy chain; Thrombin light chain
基因别名: F2; PT; RPRGL2; THPH1
UniProt ID: (Human) P00734
Entrez Gene ID: (Human) 2147
