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Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65104. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER. May play a role in cell cycle checkpoint control. Essential for telomere length control.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HsRINT-1; RAD50 interactor 1; RAD50-interacting protein 1
基因别名: RINT-1; RINT1
UniProt ID: (Human) Q6NUQ1
Entrez Gene ID: (Human) 60561