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Highest antigen sequence indentity to the following orthologs: Mouse (%), Rat (%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65014. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B. Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E3 ubiquitin-protein ligase RNF220; RING finger protein 220; RING-type E3 ubiquitin transferase RNF220
基因别名: C1orf164; RNF220
UniProt ID: (Human) Q5VTB9
Entrez Gene ID: (Human) 55182