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Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65309. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ciliogenesis and planar polarity effector 2; miro domain-containing protein C1orf89; Rem/Rab-Similar GTPase 1; REM2 and RAB-like small GTPase 1; REM2- and Rab-like small GTPase 1
基因别名: C1orf89; CPLANE2; RSG1
UniProt ID: (Human) Q9BU20
Entrez Gene ID: (Human) 79363