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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61724. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 2310075M17Rik; GTBPB; GTP-binding protein B; GTP-binding protein Sara; SAR1 homolog B; SAR1a gene homolog 2; secretion associated, Ras related GTPase 1B; Secretion-associated Ras-related GTPase 1B; Small COPII coat GTPase SAR1B
基因别名: ANDD; CMRD; GTBPB; SAR1B; SARA2; SARB
UniProt ID: (Human) Q9Y6B6
Entrez Gene ID: (Human) 51128