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Highest antigen sequence indentity to the following orthologs: Mouse (78%), Rat (78%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65497. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778). Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. Also catalyzes an electroneutral exchange of tricarboxylate, dicarboxylate, or phosphoenolpyruvate across the mitochondrial inner membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Sideroflexin-3
基因别名: BA108L7.2; SFX3; SFXN3
UniProt ID: (Human) Q9BWM7
Entrez Gene ID: (Human) 81855