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产品信息
RP-103317
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
QGSLRKGRSSMRKNGSLQRPLQSGIPTLVVGSLRRSPTMVLRPQQFQFYQPQGIPSSPSAVVVEMGSKPALTGEPALTCISRGSE
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (76%), Rat (76%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63527. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The SH3RF2 gene encodes a protein that has been shown to possess protein phosphatase 1 binding activity and ubiquitin protein ligase activity. This protein is involved in several cellular processes, including the positive regulation of the JNK cascade, protein autoubiquitination, and regulation of cellular protein metabolic processes. The protein is located in the nucleoplasm and mutations in the SH3RF2 gene have been associated with Ureter Transitional Cell Carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E3 ubiquitin-protein ligase SH3RF2; Heart protein phosphatase 1-binding protein; HEPP1; phosphatase 1 binding protein; POSH-eliminating RING protein; Protein phosphatase 1 regulatory subunit 39; protein phosphatase 1, regulatory subunit 39; RING finger protein 158; RING-type E3 ubiquitin transferase SH3RF2; SH3 domain-containing RING finger protein 2
基因别名: HEPP1; POSH3; POSHER; PPP1R39; RNF158; SH3RF2
UniProt ID: (Human) Q8TEC5
Entrez Gene ID: (Human) 153769
