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Highest antigen sequence indentity to the following orthologs: Mouse (77%), Rat (77%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61827. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protein expressed in Activated Lymphocytes; SHC SH2 domain-binding protein 1; SHC SH2-domain binding protein 1
基因别名: PAL; SHCBP1
UniProt ID: (Human) Q8NEM2
Entrez Gene ID: (Human) 79801