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This peptide corresponds to 14 amino acid peptide near the amino terminus of human SLAIN2.
PEP-1458 can be used as a blocking peptide with polyclonal antibody PA5-34416.
SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ21611; SLAIN motif family, member 2; SLAIN motif-containing protein 2
基因别名: KIAA1458; SLAIN2
UniProt ID: (Human) Q9P270
Entrez Gene ID: (Human) 57606