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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-64897. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Signal peptide peptidase (SPP) is an aspartyl protease that mediates clearance of signal peptides by proteolysis within the endoplasmic reticulum (ER). Like presenilins, SPP contains a critical GXGD motif in its C-terminal catalytic center. SPPL3 is one of several presenilin homologues/SPP-like proteins (PSHs/SPPL) that have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: IMP-2; Intramembrane protease 2; Presenilin homologous protein 1; Presenilin-like protein 4; PSH1; Signal peptide peptidase-like 3; SPP-like 3
基因别名: IMP2; MDHV1887; PRO4332; PSH1; PSL4; SPPL3
UniProt ID: (Human) Q8TCT6
Entrez Gene ID: (Human) 121665