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Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53294. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
TES maps to a common fragile site on chromosome 7q31.2 designated FRA7G and this gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. Multiple protein isoforms are encoded by transcript variants of the TES gene and Cancer-associated chromosomal changes often involve regions containing fragile sites involving the TES gene.
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蛋白别名: TESS; Testin; testis derived transcript (3 LIM domains)
基因别名: TES; TESS; TESS-2
UniProt ID: (Human) Q9UGI8
Entrez Gene ID: (Human) 26136