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This peptide corresponds to 15 amino acids near the amino terminus of human TMEM106B.
PEP-1396 can be used as a blocking peptide with polyclonal antibody PA5-34353.
Transmembrane protein 106B (TMEM106B) is a single-pass transmembrane protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual role of TMEM106B, and that of the closely related protein TMEM106A are still undetermined.
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蛋白别名: Transmembrane protein 106B
基因别名: TMEM106B
UniProt ID: (Human) Q9NUM4
Entrez Gene ID: (Human) 54664