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Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54525. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
TTLL11 is a polyglutamase which preferentially modifies alpha-tubulin. It is involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. TTLL11 is required for CCSAP localization to both spindle and cilia microtubules.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Tubulin polyglutamylase TTLL11; tubulin tyrosine ligase like11; tubulin tyrosine ligase-like family member 11; tubulin tyrosine ligase-like family, member 11; Tubulin--tyrosine ligase-like protein 11
基因别名: bA244O19.1; C9orf20; TTLL11
UniProt ID: (Human) Q8NHH1
Entrez Gene ID: (Human) 158135