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Highest antigen sequence indentity to the following orthologs: Mouse (41%), Rat (41%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62599. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization and protein polyglutamylation. Predicted to act upstream of or within microtubule bundle formation; microtubule severing; and positive regulation of cilium movement. Located in ciliary basal body.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protein polyglutamylase TTLL6; TTLL6; Tubulin polyglutamylase TTLL6; tubulin tyrosine ligase-like family member 6; Tubulin--tyrosine ligase-like protein 6
基因别名: TTL.6; TTLL6
UniProt ID: (Human) Q8N841
Entrez Gene ID: (Human) 284076