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Highest antigen sequence indentity to the following orthologs: Mouse (70%), Rat (70%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58691. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Related to the N-terminus of tre; RN-tre; USP6 N-terminal-like protein
基因别名: KIAA0019; RNTRE; TRE2NL; USP6NL; USP6NL-IT1
UniProt ID: (Human) Q92738
Entrez Gene ID: (Human) 9712