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产品信息
RP-104239
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
GKKPKETYGGSDLREDAIAPGISEHTCMRADSSKGFLERPSSASTVTTTKSKLPMVV
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (70%), Rat (70%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62144. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
CTXL, a cortical thymocyte marker, is a member of the immunoglobulin (Ig) superfamily and has features of both antigen specific receptors and adhesion molecules. This single pass, type I protein contains a signal peptide, an extracellular V type Ig like domain followed by a C2 type Ig like domain and a cytoplasmic tail. Expression levels of CTXL are high in the stomach, colon, prostate, trachea, and thyroid gland, with lower levels observed in bladder and lung tissues. CTXL is not expressed in the thymus. CTXL is developmentally regulated and may be involved in thymocyte selection. It localizes to junctional complexes between endothelial and epithelial cells and may play a role in cell-cell adhesion and transmigration of leukocytes.
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生物信息学
蛋白别名: cortical thymocyte receptor (X. laevis CTX) like; Cortical thymocyte-like protein; CT-like protein; V-set and immunoglobulin domain-containing protein 2
基因别名: 2210413P10Rik; CTH; CTXL; UNQ2770/PRO7154; VSIG2
UniProt ID: (Human) Q96IQ7
Entrez Gene ID: (Human) 23584
