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Highest antigen sequence indentity to the following orthologs: Mouse (46%), Rat (46%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62627. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in normal testis, and in Ewing's sarcoma, rhabdomyosarcoma, a breast cancer and a germ cell tumor. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cancer/testis antigen 12.2; cancer/testis antigen family 12, member 2; CT12.2; G antigen family D member 3; X antigen family member 2; X antigen family, member 2; X antigen family, member 2B; XAGE-2
基因别名: CT12.2; GAGED3; XAGE-2; XAGE2; XAGE2B
UniProt ID: (Human) Q96GT9
Entrez Gene ID: (Human) 9502