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产品信息
RP-107414
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
RASITDPGRLPENPKIPHGEREFWELCNKCNLMRPKRSHHCSRCGHCVRRM
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66757. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptor. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DHHC domain-containing cysteine-rich protein 21; DHHC-21; Palmitoyltransferase ZDHHC21; probable palmitoyltransferase ZDHHC21; Zinc finger DHHC domain-containing protein 21; zinc finger, DHHC domain containing 21; zinc finger, DHHC-type containing 21
基因别名: 9130404H11Rik; DHHC-21; DHHC21; DNZ1; HSPC097; ZDHHC21
UniProt ID: (Human) Q8IVQ6
Entrez Gene ID: (Human) 340481
