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Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66653. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Component or associated component of some histone methyltransferase complexes may regulate transcription through recruitment of those complexes on gene promoters. Enhances ligand-dependent transcriptional activation by nuclear hormone receptors. Plays an important role in neural progenitor cell proliferation and self-renewal through the regulation of specific genes involved brain development, including REST. Also controls the expression of genes involved in somatic development and regulates, for instance, lymphoblast proliferation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: NIF-1; NRC-interacting factor 1; Zinc finger protein 335; zinc-finger/leucine-zipper co-transducer NIF1
基因别名: MCPH10; NIF-1; NIF1; NIF2; ZNF335
UniProt ID: (Human) Q9H4Z2
Entrez Gene ID: (Human) 63925