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Highest antigen sequence indentity to the following orthologs: Mouse (38%), Rat (38%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-140015. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
ZNF446 contains a KRAB and three C(2)H(2) zinc fingers. ZNF446 is a transcription repressor when fused to GAL4 DNA-binding domain and co-transfected with VP-16. Overexpression of ZNF446 in COS-7 cells inhibits the transcriptional activities of SRE.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ20626; Zinc finger protein 446; Zinc finger protein with KRAB and SCAN domains 20
基因别名: ZKSCAN20; ZNF446; ZSCAN30; ZSCAN52
UniProt ID: (Human) Q9NWS9
Entrez Gene ID: (Human) 55663