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产品信息
PMC1474
应用
建议稀释比
已发表文章
产品规格
种属
Mouse
Expression System
E. coli
氨基酸序列
Mouse CCL21 recombinant protein contains 110 amino acids
分子量
12 kDa
分类
Recombinant
类型
Protein
纯度
≥98% by SDS-PAGE and HPLC
内毒素浓度
<0.1 ng/µg
活性
ED50 = 10 - 100 ng/mL; determined by the dose-dependent chemotaxis of human activated T-cells in the presence of IL-2.
偶联物
形式
Lyophilized
纯化类型
purified
内含物
no preservative
保存条件
-20°C
运输条件
Wet ice (domestic); Wet or Dry ice (international)
产品详细信息
Carrier-Free
Reconstitution: We recommend that the vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute this protein in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Do not vortex. Further dilutions should be made in aqueous buffers supplemented with carrier protein, such as 0.1-1.0% BSA.
Storage: This lyophilized preparation is stable at room temperature for 1 month, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2°C to 8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -80°C for 3months. Avoid repeated freeze/thaw cycles
靶标信息
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 6 Ckine; 6Ckine; beta chemokine exodus-2; Beta-chemokine exodus-2; C-C motif chemokine 21a; C-C motif chemokine 21b; C-C motif chemokine 21c; CC chemokine 6Ckine-ser; Ccl21-leu; CCL21-Ser; exodus-2; secondary lymphoid organ chemokine; small inducible cytokine A21; small inducible cytokine A21a; small inducible cytokine A21c; Small-inducible cytokine A21a; Small-inducible cytokine A21b; Small-inducible cytokine A21c; TCA4; Thymus-derived chemotactic agent 4
基因别名: 6CKBAC1; 6CKBAC2; 6Ckine; AI159701; ALP; AW987545; Ccl21a; Ccl21b; Ccl21c; CKb9; exodus-2; plt; Scya21; SCYA21a; Scya21b; Scya21c; SLC; TCA4
UniProt ID: (Mouse) P84444, (Mouse) P86792
Entrez Gene ID: (Mouse) 18829, (Mouse) 100042493, (Mouse) 65956
