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产品信息
RP-88232
产品规格
种属
Mouse
Expression System
HEK293 cells
氨基酸序列
Mouse EPHA3, amino acids Met1-His541 (Accession # NP_034270.1) with a C-terminal His-tag
标签
His-tag
分子量
60.2 kDa
分类
Recombinant
类型
Protein
纯度
>95% as determined by SDS-PAGE.
内毒素浓度
<1.0 EU/µg
活性
1. Measured by its binding ability in a functional ELISA. 2. Immobilized mouse EPHA3-His at 10 µg/mL (100 µL/well) can bind mouse EFNA5-Fc . The EC50 of mouse EFNA5-Fc is 4.9-11.4 ng/mL.
偶联物
形式
Lyophilized
纯化类型
purified
保存液
PBS, pH 7.4, with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
It is recommended that the protein be aliquoted for optimal storage.
It is recommended that sterile water (800 µL) be added to the vial to prepare a stock solution of 0.25 mg/mL.
Concentration is measured by UV.
靶标信息
EPHA3 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA3 encodes a protein that binds ephrin-A ligands and receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 binds ephrin-A ligands.
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生物信息学
蛋白别名: EK4; EPH-like kinase 4; ephrin type-A receptor 3; H TYRO4; tyrosine-protein kinase receptor ETK1; tyrosine-protein kinase TYRO4
基因别名: AW492086; Cek4; End3; ETK1; Hek; Hek4; Mek4; Tyro4
Entrez Gene ID: (Mouse) 13837
