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产品信息
RP-88271
产品规格
种属
Rat
Expression System
HEK293 cells
氨基酸序列
Rat B7-H6, amino acids Met1-Ser308 (Accession # XP_006223356.1) with a C-terminal His-tag
标签
His-tag
分子量
35.1 kDa
分类
Recombinant
类型
Protein
纯度
>95% as determined by SDS-PAGE.
内毒素浓度
<1.0 EU/µg
偶联物
形式
Lyophilized
纯化类型
purified
保存液
PBS, pH 7.4, with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
It is recommended that the protein be aliquoted for optimal storage.
It is recommended that sterile water (200 µL) be added to the vial to prepare a stock solution of 0.25 mg/mL.
Concentration is measured by UV.
靶标信息
B7-H6 (NCR3LG1) is a transmembrane endogenous ligand expressed on the surfaces of tumor cells. B7-H6 binds with NKp30 present on NK cells. Binding of B7-H6 to NKp30 causes the ligation of NKp30 subsequently inducing NK cell activation and target cell cytolysis. B7-H6 is not constitutively expressed on normal tissue. Whether it can be expressed endogenously under certain conditions is under investigation. B7-H6 has been detected on circulating pro-inflammatory CD14(+)CD16(+) monocytes in some patients with sepsis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp686I21167; natural killer cell cytotoxicity receptor 3 ligand 1
Entrez Gene ID: (Rat) 691092
