Invitrogen

Rat RAB3d (aa 1-18) Synthetic Peptide

说明书

技术支持

说明书

技术支持

产品信息

PEP-144

应用

建议稀释比

已发表文章

对照试剂 (Ctrl)

Assay-dependent

产品规格

种属反应

Rat

分类

Synthetic

类型

Peptide

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.5 mg/mL

纯化类型

purified

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

产品详细信息

PEP-144 is an 18 amino acid synthetic peptide whose sequence corresponds to residues 1-18 from rat rab 3D. The sequence of this peptide is (amino to carboxy terminus): M (1)-A-S-A-S-E-P-P-A-S-P-R-D-A-A-D-Q-N (18)

This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat rab 3D, catalog # PA1-773. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.

Reconstitute with 0.1 mL of distilled water.

靶标信息

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 rab proteins that have been described in mammals. Rab 3D has been shown to be present, in part, in the tongue, pancreas, and liver.

仅用于科研。不用于诊断过程。未经明确授权不得转售。