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Human TIMP-1 quantitates human TIMP-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human TIMP-1.
TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CLGI, EPA, EPO, HCI, TIMP, TIMP-1, TIMP1
基因ID : (Human) 7076
基因符号 : TIMP1
蛋白别名 : Collagenase inhibitor, EPA, erythroid potentiating activity, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, FLJ90373, RP1-230G1.3, TIMP 1, Metalloproteinase inhibitor, MMP inhibitor, Metalloproteinase inhibitor 1, TIMP-1, Tissue inhibitor of metalloproteinases 1
UniProt ID (Human) P01033