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900-K49K consists of: 900-K49 (capture antibody, detection antibody, and protein standard), and AVIDIN-60UL (avidin HRP-conjugate).
Mouse IL-4 ABTS ELISA Development Kit contains the key components required for the quantitative measurement of natural and/or recombinant mouse IL-4 in a sandwich ELISA format. Mouse IL-4 ABTS ELISA Development Kit contains enough material to assay the target cytokine in at least 1,000 ELISA plate wells.
The ABTS ELISA Buffer Kit (Product # 900-K00), sold separately, is recommended to be used in conjunction with this ABTS ELISA Development Kit for optimal performance. This buffer kit contains all the necessary components to assay ten 96-well ELISA plates (included) and contains detailed handling instructions.
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : BSF-1, Il-4, Il4
基因ID : (Mouse) 16189
基因符号 : Il4
蛋白别名 : B-cell growth factor 1, B-cell IgG differentiation factor, B-cell stimulatory factor 1, BSF-1, H-IL-4, MGC79402, M-IL-4, ILN, Interleukin, Interleukin4, IGG1 induction factor, IL-4, Interleukin-4, Lymphocyte stimulatory factor 1
UniProt ID (Mouse) P07750