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产品规格
检测灵敏度
9.38 pg/mL
测定范围
15.63-1000 pg/mL
检测样本类型/体积
{Cell Lysate=100 µL, Plasma=100 µL, Serum=100 µL, Tissue Homogenate=100 µL}
手工操作时间
1 hr 20 min
总时间
2 hr 30 min
均相（无需洗涤）
No
批间差异
<10%
批内差异
<10%
检测仪器
Colorimetric Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate, Standard, Biotinylated Detection Antibody, HRP Conjugate, Standard & Sample Diluent, Biotinylated Detection Antibody Diluent, HRP Conjugate Diluent, Wash Buffer, TMB Substrate, Stop Solution, Plate Sealer
储存
Refer to product documentation for component specific storage temperature.
蛋白名称
alpha Synuclein
均相（无需洗涤）
Mouse
Species (reported)
Mouse
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
Unconjugated
关于本试剂盒
The Mouse Synuclein alpha (SNCalpha) ELISA quantitates SNCalpha in serum, plasma and other biological fluids.
原理方法
The Mouse Synuclein Alpha (SNCa) solid phase sandwich ELISA (enzyme linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target specific antibody has been pre coated in the wells of the supplied microplate. Samples are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the binding of the second (detector) antibody to the target on a different epitope from the capture antibody. An antibody conjugated with enzyme binds the formed sandwich. After incubation and washing steps to rid the microplate of unbound substances.
Rigorous validation:
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
靶标信息
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking. Alpha- and beta-synuclein have been shown to selectively inhibit phospholipase D2, suggesting that they may also be involved in signaling pathways. Defects in the SNCA gene, which encodes alpha-synuclein, have been implicated in the pathogenesis of Parkinson's disease. Additionally, alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene. Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant and Dementia, Lewy Body.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : alphaSYN, NACP, Snca, Syn
基因ID : (Mouse) 20617
基因符号 : Snca
蛋白别名 : Alpha synuclein, Alpha-synuclein, NACP, Non-A beta component of AD amyloid, non-A4 component of amyloid, Non-A4 component of amyloid precursor
UniProt ID (Mouse) O55042
