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产品规格
检测灵敏度
2 pg/mL
测定范围
2-600 pg/mL
检测样本类型/体积
{Supernatant=50 µL, Plasma=50 µL, Serum=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Colorimetric Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
2-8°C
蛋白名称
TNFR1
均相（无需洗涤）
Rat
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Rat TNF R1 quantitates rat TNF R1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat TNF R1.
靶标信息
TNFR1 (Tumor necrosis factor receptor 1) belongs to the tumor necrosis factor superfamily, and is one of the major TNF-alpha receptors. TNFR1 plays an important role in mediating, in cytokine mediated signaling, positive regulation of the NF-Kb pathway, positive regulation of angiogenesis, and negative regulation of gene expression. The extracellular domain of TNFR1 is also released into the circulatory system as soluble TNFR1 (sTNFR1). In humans, the TNFR1 gene is located on chromosome 12. Anti-apoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with TNFR1, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of TNFR1 were found to be associated with the autosomal dominant periodic fever syndrome, and the impaired receptor clearance is thought to be a mechanism of the disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : TNFR-1, Tnfr1, Tnfrsf1a
基因ID : (Rat) 25625
基因符号 : Tnfrsf1a
蛋白别名 : CD120a, CD120a antigen, sTNFR1, sTNFRI, TNFR, TNFR I, Tumor necrosis factor receptor, n-smase activation assoc. factor, sCD120a, soluble CD120a, soluble TNFR1, sTNF RI, sTNFR I, MGC19588, p62, p63, p55, p60, TNF-R1, TNF-RI, TNFR-I, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor type I
UniProt ID (Rat) P22934
