Invitrogen

NeuroG3 Recombinant Rabbit Monoclonal Antibody (10H35L14)

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NeuroG3 Antibody (703206) in WB

Western blot analysis was performed on modified whole cell extracts (1% SDS) (30 µg lysate) of MDAM-MB-231 (Lane 1), IMR-32 (Lane 2) and tissue extracts of Mouse Pancreas (Lane 3), Mouse Brain (Lane 4) and Mouse Pup Brain (Lane 5). The blot was probed with Anti-Neurogenin-3 Recombinant Rabbit Monoclonal Antibody (Product # 703206, 1:1,000 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4,000 dilution). A 30 kDa corresponding... View More

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产品信息

703206

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

Expression System

Expi293

分类

Recombinant Monoclonal

类型

Antibody

克隆号

10H35L14

抗原

Protein corresponding to human Neurogenin-3 [aa1-aa214]

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2762416

产品详细信息

This antibody is predicted to react with Monkey, Pig, Goat, Bovine.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

靶标信息

Neurog 3 protein contains one basic helix-loop-helix (bHLH) domain.It is both necessary and sufficient to induce endocrine islet cell differentiation from embryonic pancreatic progenitors. Not only does itinitiates endocrine cell differentiation, italso promotes islet cell maturation and maintains islet function. It is reported that Neurogenin 3 can redirect the differentiation of bipotential secretory progenitors to endocrine rather than goblet cell fate.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: atonal homolog 5; bHLHa7; Class A basic helix-loop-helix protein 7; Helix-loop-helix protein mATH-4B; mATH4B; Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B); Neurogenin-3; neurogenin3; NGN-3; Protein atonal homolog 5

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基因别名: Ath4b; ATOH5; BHLHA7; Math4B; NEUROG3; NGN-3; NGN3

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UniProt ID: (Human) Q9Y4Z2, (Mouse) P70661

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Entrez Gene ID: (Human) 50674, (Mouse) 11925

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