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产品信息
A32875
产品规格
种属
Human
Expression System
Insect cells
氨基酸序列
Full length
标签
GST-tag
分子量
62.6 kDa
分类
Recombinant
类型
Protein
偶联物
形式
Liquid
浓度
See Label
纯化类型
purified
保存液
50mM tris HCl, pH 7.5, with 10mM glutathione, 25% glycerol, 0.1mM PMSF, 0.25mM DTT, 150mM NaCl, 0.1mM EDTA
内含物
no preservative
保存条件
-80° C, Avoid Freeze/Thaw Cycles
运输条件
Dry ice
产品详细信息
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
This PIM3 recombinant human protein (full length) was expressed in insect cells.
PIM3 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the Z'-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service
Protein Form: Full Length, Recombinant, Active
The gene accession number for PIM3 is NP_663453.1.
靶标信息
PIM3 serine/threonine kinase or PIM-3 oncogene belongs to a family of protooncogenes. PIM3 is expressed in hepatocellular carcinoma development and plays a main role in the proliferation of human hepatoma cell lines. PIM3 also expressed in human pancreatic cancer cells and phosphorylates BAD to block Bad-mediated apoptosis in human pancreatic cancer cell lines. PIM3 is widely expressed, with the exception of no expression observed in colon, thymus, and small intestine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: pim-3 oncogene; serine/threonine kinase Pim-3; Serine/threonine-protein kinase pim-3
基因别名: pim-3; PIM3
UniProt ID: (Human) Q86V86
Entrez Gene ID: (Human) 415116
