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产品信息
PR7016A
产品规格
种属
Human
Expression System
Insect cells
氨基酸序列
Full length
标签
GST-tag
分子量
127.9 kDa
分类
Recombinant
类型
Protein
纯度
95% by SDS-PAGE
偶联物
形式
Liquid
浓度
See Label
纯化类型
purified
保存液
50mM tris, pH 7.5, with 150mM NaCl, 0.5mM EDTA, 2mM DTT, 50% glycerol, 0.02% Triton X-100
内含物
no preservative
保存条件
-80° C, Avoid Freeze/Thaw Cycles
运输条件
Dry ice
产品详细信息
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
Protein Form: Full Length
靶标信息
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.
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生物信息学
蛋白别名: nPKC-nu; Protein kinase C nu type; Protein kinase EPK2; Serine/threonine-protein kinase D3
基因别名: EPK2; nPKC-NU; PKC-NU; PKD3; PRKCN; PRKD3
UniProt ID: (Human) O94806
Entrez Gene ID: (Human) 23683
