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产品信息
PV6358
产品规格
种属
Human
Expression System
Baculovirus
氨基酸序列
1-632
标签
GST-tag
分子量
95.1 kDa
分类
Recombinant
类型
Protein
偶联物
形式
Liquid
浓度
See Label
纯化类型
purified
保存液
50mM tris HCl, pH 7.5, with 25% glycerol, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, 150mM NaCl, 10mM glutathione
内含物
no preservative
保存条件
-80° C, Avoid Freeze/Thaw Cycles
运输条件
Dry ice
产品详细信息
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
Full-length recombinant human ICK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
• Validated in LanthaScreen™ Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use
Related Product:
LanthaScreen™ Eu Kinase Binding Assay
Protein Form: Recombinant
The gene accession number for ICK is NP_055735.1.
靶标信息
ICK or intestinal cell kinase belongs to a very extensive family of proteins that share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. ICK encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. ICK localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. ICK purified from transfected human embryonic kidney cells undergoes autophosphorylation and phosphorylates a test protein. ICK plays a key role in development of central nervous, skeletal, and endocrine systems.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ciliogenesis associated kinase 1; hICK; Intestinal cell kinase; Laryngeal cancer kinase 2; LCK2; MAK-related kinase; MRK; serine/threonine protein kinase; Serine/threonine-protein kinase ICK
基因别名: CILK1; ECO; ICK; KIAA0936; LCK2; MRK
UniProt ID: (Human) Q9UPZ9
Entrez Gene ID: (Human) 22858
