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产品信息
RP-87667
应用
建议稀释比
已发表文章
产品规格
种属
Virus
Expression System
E. coli
氨基酸序列
SARS-CoV-2 ORF3a, amino acids 126-275
分子量
22 kDa
分类
Recombinant
类型
Protein
纯度
>95% by reducing SDS-PAGE
偶联物
形式
Liquid
浓度
1.8 mg/mL
纯化类型
purified
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
Purity is > 95% by SDS-PAGE.
靶标信息
ORF3A forms homotetrameric potassium sensitive ion channels (viroporin) and may modulate virus release. Up-regulates expression of fibrinogen subunits FGA, FGB and FGG in host lung epithelial cells. Induces apoptosis in cell culture. Downregulates the type 1 interferon receptor by inducing serine phosphorylation within the IFN alpha-receptor subunit 1 (IFNAR1) degradation motif and increasing IFNAR1 ubiquitination.
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生物信息学
蛋白别名: COVID-19 ORF3A; COVID19 ORF3A; ORF3A; SARS-CoV-2 Open Reading Frame 3A; SARS-COV2 ORF3A
