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LOADING
See other TP53 SIRNA Assays ›
Gene Symbol:
TP53
Gene Name:
tumor protein p53
Gene Aliases:
BCC7, LFS1, P53, TRP53
Chromosome Location:
Chr.17: 7668402 - 7687550 on Build GRCh38
UniGene ID:
Hs.437460
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID
HSS110905
Size
20 nmol
20 nmol
Availability
Made To Order
Catalog #
1299001
Price
Your Price
Online offer:
Check your price ›
添加到购物车
Genomic Map
siRNA Details
More Information
Genomic Map
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siRNA Details
Gene Symbol: TP53
Interrogated Sequence
Translated Protein
Targeted Exon(s)
siRNA Location
IMAGE Clone ID
RefSeq
NM_000546.5
NP_000537.3
10
1222
NM_001126112.2
NP_001119584.1
10
1219
NM_001126113.2
NP_001119585.1
11
1282
NM_001126114.2
NP_001119586.1
11
1355
NM_001126115.1
NP_001119587.1
6
902
NM_001126116.1
NP_001119588.1
7
1035
NM_001126117.1
NP_001119589.1
7
962
NM_001126118.1
NP_001119590.1
9
1339
NM_001276695.1
NP_001263624.1
11
1282
NM_001276696.1
NP_001263625.1
11
1355
NM_001276697.1
NP_001263626.1
6
902
NM_001276698.1
NP_001263627.1
7
1035
NM_001276699.1
NP_001263628.1
7
962
NM_001276760.1
NP_001263689.1
10
1222
NM_001276761.1
NP_001263690.1
10
1219
GenBank mRNA
AB082923.1
-
10
1083
AF307851.1
-
10
1155
AK223026.1
-
4
315
AK225838.1
-
10
1160
AK297462.1
-
11
1087
AK297927.1
-
11
1132
AK312568.1
-
10
1164
AM076970.1
-
9
987
AY429684.1
-
9
1020
BC003596.1
-
10
1140
3544714
BT019622.1
-
9
1020
DQ186648.1
-
11
1285
DQ186649.1
-
11
1212
DQ186650.1
-
6
898
DQ186651.1
-
7
1031
DQ186652.1
-
7
958
DQ191317.1
-
10
1209
DQ263704.1
-
9
1020
DQ286964.1
-
10
1154
DQ648886.1
-
2
96
EF101867.1
-
9
987
FJ207420.1
-
10
1155
JN214348.1
-
9
1065
JN601513.1
-
9
1020
JN601514.1
-
9
1020
JN601515.1
-
9
1020
JN601516.1
-
10
994
JN900492.1
-
9
1328
JQ026207.1
-
9
1010
JQ026208.1
-
9
1015
JQ026209.1
-
9
1025
JQ026210.1
-
9
1015
JQ694049.1
-
9
1043
JQ694050.1
-
9
1043
JQ694051.1
-
9
1043
M14694.1
-
10
1145
M14695.1
-
10
1141
X01405.1
-
7
721
X02469.1
-
10
1155
X60011.1
-
9
1020
X60012.1
-
9
1020
X60013.1
-
9
1020
X60014.1
-
9
1020
X60015.1
-
9
1020
X60016.1
-
9
1020
X60017.1
-
9
1020
X60018.1
-
9
1020
X60019.1
-
9
1020
X60020.1
-
9
1020
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More Information
Other Species Targeted
This siRNA also targets the following transcripts in Rat: NM_030989, XM_006246594, XM_006246595, XM_003749209, XM_008767773, and others.
Gene Ontology Categories:
Function(s)
Process(es)
negative regulation of transcription from RNA polymerase II promoter
DNA strand renaturation
base-excision repair
nucleotide-excision repair
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein complex assembly
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
ER overload response
cell cycle arrest
Ras protein signal transduction
multicellular organism development
cell aging
protein localization
cell proliferation
negative regulation of cell proliferation
determination of adult lifespan
response to X-ray
response to gamma radiation
positive regulation of gene expression
viral process
protein sumoylation
cell differentiation
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
positive regulation of histone deacetylation
chromatin assembly
mitotic G1 DNA damage checkpoint
positive regulation of protein oligomerization
cellular response to UV
cellular response to drug
cellular response to glucose starvation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
entrainment of circadian clock by photoperiod
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to antibiotic
positive regulation of protein export from nucleus
regulation of mitochondrial membrane permeability
negative regulation of fibroblast proliferation
circadian behavior
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of helicase activity
protein tetramerization
negative regulation of telomerase activity
positive regulation of thymocyte apoptotic process
positive regulation of cell cycle arrest
cellular response to hypoxia
cellular response to ionizing radiation
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of release of cytochrome c from mitochondria
replicative senescence
oxidative stress-induced premature senescence
intrinsic apoptotic signaling pathway
oligodendrocyte apoptotic process
positive regulation of execution phase of apoptosis
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
regulation of cell cycle G2/M phase transition
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
positive regulation of reactive oxygen species metabolic process
positive regulation of intrinsic apoptotic signaling pathway
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protease binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
copper ion binding
protein binding
ATP binding
transcription factor binding
zinc ion binding
enzyme binding
protein kinase binding
protein phosphatase binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
histone acetyltransferase binding
identical protein binding
sequence-specific DNA binding
protein self-association
transcription regulatory region DNA binding
protein heterodimerization activity
protein N-terminus binding
chaperone binding
protein phosphatase 2A binding
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