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产品信息
RP-38966
产品规格
Expression System
E. coli
分类
Recombinant
类型
Protein
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
产品详细信息
This product is a GST-tagged recombinant protein corresponding to human CD23, aa 48-248.
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 48kDa.
靶标信息
CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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