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Highest antigen sequence indentity to the following orthologs: Mouse (35%), Rat (35%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111197. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Alpha-1-B glycoprotein (A1BG) which is a plasma protein with no known function belongs to the immunoglobulin superfamily. Although the human A1BG has been known for four decades, and the information about the amino acid sequence, chromosomal assignment, and even genetic polymorphism in different populations have been known, no biological function has been suggested. A1BG (Mr approximately equal to 63,000) consists of one polypeptide chain of 474 amino acids with four glucosamine oligosaccharides. The polypeptide has five intrachain disulfide bonds and consists of five repeating structural domains, each containing about 95 amino acids and one disulfide bond. Recently human cysteine-rich secretory protein 3 (CRISP-3) has been found to be a binding partner of A1B, suggesting the A1BG-CRISP-3 complex displays a protecting function from a potentially harmful effect of free CRISP-3 in circulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Alpha-1-B glycoprotein; alpha-1-B-glycoprotein; Alpha-1B-glycoprotein; alpha1B-glycoprotein; DKFZp686F0970; epididymis secretory sperm binding protein Li 163pA; HEL-S-163pA
基因别名: A1B; A1BG; ABG; GAB; HYST2477
UniProt ID: (Human) P04217
Entrez Gene ID: (Human) 1