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产品信息
RP-107383
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
LYFDKILPYGDERHYSPLFFLNSSSCFQHQRTNAKVIEKEIDAEHPSDDYF
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (59%), Rat (59%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66731. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The ATP-binding cassette (ABC) superfamily is comprised of transmembrane proteins involved in energy-dependent transport of a variety of substrates across membranes. ABCA6 is a 1,617 amino acid protein belonging to the ABC transporter family. ABCA6 is up-regulated during monocyte differentiation into macrophages, suggesting a role in macrophage lipid homeostasis. ABCA6 contains two ABC transporter domains and is expressed as three isoforms produced by alternative splicing. ABCA6 is present at highest levels in adult liver, with significant levels found in many adult tissues and fetal lung, kidney and liver.
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生物信息学
蛋白别名: ABC transporter ABCA6; ATP-binding cassette A6; ATP-binding cassette sub-family A member 6; ATP-binding cassette, sub-family A (ABC1), member 6
基因别名: ABCA6; EST155051
UniProt ID: (Human) Q8N139
Entrez Gene ID: (Human) 23460
