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Highest antigen sequence indentity to the following orthologs: Mouse (91%), Rat (91%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65610. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. Alternative splicing results in several transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 22; ADAM; ADAM 22; ADAMs; Disintegrin and metalloproteinase domain-containing protein 22; metalloendopeptidases; Metalloproteinase-disintegrin ADAM22-3; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2; MGC149832
基因别名: ADAM 22; ADAM22; MDC2
UniProt ID: (Human) Q9P0K1
Entrez Gene ID: (Human) 53616