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Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56399. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Aging-associated gene 5 protein; aging-associated protein 5; Alkyl-DHAP synthase; Alkyldihydroxyacetonephosphate synthase, peroxisomal; Alkylglycerone-phosphate synthase
基因别名: AAG5; ADAP-S; ADAS; ADHAPS; ADPS; AGPS; ALDHPSY; RCDP3
UniProt ID: (Human) O00116
Entrez Gene ID: (Human) 8540