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Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55734. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
AIDA acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Axin interaction partner and dorsalization antagonist; Axin interactor, dorsalization-associated protein
基因别名: AIDA; C1orf80
UniProt ID: (Human) Q96BJ3
Entrez Gene ID: (Human) 64853