Search Thermo Fisher Scientific
Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57633. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a GTPase-activating protein (GAP). A variety of cellular processes are regulated by Rho GTPases which cycle between an inactive form bound to GDP and an active form bound to GTP. This cycling between inactive and active forms is regulated by guanine nucleotide exchange factors and GAPs. The encoded protein is a GAP shown to regulate two GTPases involved in protein trafficking and cell growth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cdc42 GTPase-activating protein; Rho GTPase-activating protein 31
基因别名: AOS1; ARHGAP31; CDGAP; KIAA1204
UniProt ID: (Human) Q2M1Z3
Entrez Gene ID: (Human) 57514