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Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111413. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a Rho-like GTPase that switches between the active state and inactive state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy, also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cdc42 guanine nucleotide exchange factor (GEF) 9; Collybistin; hPEM-2 collybistin; PEM-2 homolog; Rac/Cdc42 guanine nucleotide exchange factor 9; Rho guanine nucleotide exchange factor 9
基因别名: ARHDH9; ARHGEF9; COLLYBISTIN; EIEE8; HPEM-2; KIAA0424; PEM-2; PEM2
UniProt ID: (Human) O43307
Entrez Gene ID: (Human) 23229