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Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82149. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
ARPC1A is one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: actin binding protein (Schizosaccharomyces pombe sop2-like); actin related protein 2/3 complex subunit 1A, 41kDa; actin related protein 2/3 complex, subunit 1A, 41kDa; Actin-related protein 2/3 complex subunit 1A; ARC1A; epididymis luminal protein 68; epididymis secretory protein Li 307; SOP2-like protein
基因别名: Arc40; ARPC1A; HEL-68; HEL-S-307; SOP2Hs; SOP2L
UniProt ID: (Human) Q92747
Entrez Gene ID: (Human) 10552