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产品信息
PHC7204
应用
建议稀释比
已发表文章
产品规格
种属
Human
Expression System
CHO cells
氨基酸序列
Human BMP-7 recombinant protein is a homodimer containing two 117 amino acid subunits (BMP-7, amino acids 315-431)
分子量
28.8 kDa
分类
Recombinant
类型
Protein
纯度
≥98% by SDS-PAGE and HPLC
内毒素浓度
<0.1 ng/µg
活性
ED50 = 0.02 - 0.04 ng/mL; determined by the dose-dependent induction of alkaline phosphatase in mouse ATDC52 chondrogenic cells.
偶联物
形式
Lyophilized
纯化类型
purified
内含物
no preservative
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Carrier-Free
Reconstitution: Centrifuge the vial briefly, before opening to bring the contents to the bottom. Reconstitute the lyophilized protein in sterile, distilled water, to a concentration of 0.1-1.0 mg/mL (Do not vortex) and store at 2-8°C for up to 1 week. Make any further dilutions of the reconstituted protein in buffer containing carrier protein, such as 0.1% BSA, and apportion into working aliquots to store at -20°C to -80°C.
Storage: The lyophilized protein is stable at room temperature for 1 month. Store the lyophilized protein at -20°C to -80°C,preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. Working aliquots stored with a carrier protein are stable for at least 7 months at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
靶标信息
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BMP; BMP-7; Bone morphogenetic protein; Bone morphogenetic protein 7; OP-1; Osteogenic protein 1; RP11-560A15.5
基因别名: BMP7; OP-1; OP1
UniProt ID: (Human) P18075
Entrez Gene ID: (Human) 655
