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产品信息
RP-87951
产品规格
种属
Human
Expression System
HEK293 cells
氨基酸序列
Human ANGPT1, amino acids Met1-Leu261 and Arg277-Phe498 linked by a polypeptide linker (Accession # NP_001137.2) with a C-terminal human IgG1 Fc region
标签
Fc-tag
分子量
82 kDa
分类
Recombinant
类型
Protein
纯度
>85% as determined by SDS-PAGE.
内毒素浓度
<1.0 EU/µg
偶联物
形式
Lyophilized
纯化类型
purified
保存液
PBS, pH 7.4, with <0.1µg/mL BSA, 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
It is recommended that the protein be aliquoted for optimal storage.
It is recommended that sterile water (1493 µL) be added to the vial to prepare a stock solution of 0.67 mg/mL.
Concentration is measured by UV.
靶标信息
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.
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生物信息学
蛋白别名: ANG-1; Angiopoietin-1
基因别名: AGP1; AGPT; ANG1; ANGPT1; KIAA0003
UniProt ID: (Human) Q15389
Entrez Gene ID: (Human) 284
