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This peptide corresponds to 14 amino acids near the amino terminus of human BCAS4.
PEP-1021 can be used as a blocking peptide with polyclonal antibody PA5-20907.
The Breast carcinoma amplified sequence (BCAS4) gene is localized to 20q13, a region that is often amplified in breast cancers. It was isolated by the cloning of a highly overexpressed 1.3 kb transcript from the fusion of the last two exons of the BCAS3 and BCAS4 genes. This BCAS3-BCAS4 fusion transcript is only found in the MCF7 cell line, but the BCAS4 gene is also overexpressed in nine of thirteen breast cancer cell lines. The role of BCAS4 is unknown but its mRNA is highly expressed in thymus, spleen, kidney, brain, and placenta, suggesting BCAS4 plays other roles in multiple tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BCAS4/BCAS3 fusion; breast carcinoma amplified sequence 4/3 fusion protein; Breast carcinoma-amplified sequence 4; RP5-1071L10.2
基因别名: BCAS4; CNOL
UniProt ID: (Human) Q8TDM0
Entrez Gene ID: (Human) 55653